An evil angel named Gabriel created "Alternates." Alternates are shapeshifting monsters who have taken over the entire U.S.A. But then, an anthropomorphic animal infection came in to save people. It allowed humans to use their teeth and animal urges to make alternates endangered. People love being anthropomorphic animals since they have better strength and speed, have fluffy tails to wag, and they can nuzzle. They plan to finally take down Gabriel.