As expected of a nurse, Sayuri is extremely caring and friendly, often showing concern for the health of others and taking care of them, or offering advice on how to take better care of themselves. Similar to Tamaki and Momiji, she has a sisterly demeanor, although to a much greater extent, even referring to herself as "Big Sis" ("onee-chan" in the Japanese version) when talking to others. She implies that this demeanor is a holdover from her previous nursing job.