16 high-school students being forced into a mutual killing game. Each character has a special skill or ability, known as an Ultimate Talent. The game follows Kaede Akamatsu, Shuichi Saihara, and fourteen other high school students with special talents who are trapped in a killing game where the culprit must avoid suspicion from the other students such as Kokichi, Himiko, Maki, Korekiyo, Kaito, Rantaro, Tenko, Gonta, Miu, Angie, Kirumi, Ryoma, Tsumugi, and K1-B0 or be executed