Iroha Nijue is a young girl who survived a killing game. In the past, she was a talented painter and now a symbol of Despair of the New Generation. She is the "Queen of Despair" and the head of the organization of Ultimate Despair. But in fact, she remained a stupid, cowardly and nervous girl. She tries to look cool so that people can more easily give offerings when joining the organization. In the end, she doesn't want to take this place, but she can't do otherwise, because she needs money.