Darla Dimple is a villainous child star of Hollywood who conceals her true nature from her fans through a facade of sweetness.
Princess Morbucks is a spoiled rich girl who hates the Powerpuff Girls due to envy.
Suzy Johnson appears very sweet, but is very spoiled and manipulative and very possessive over her old brother Jeremy.
Aquamarine is an alien whose innocent looks contrasts with her ruthless and sadistic personality.
Baby Doll is an actress who became bitter after falling into obscurity.

Darla, Princess, Suzy, Aquamarine, and Baby Doll

15-year-old. Outgoing and mostly fearless (only afraid of wax figures and olms.) Loves adventure, monsters, and her family. Explosive and unpredictable. Dislikes being babied. Has a friendly rivalry with her older brother Sprig. Stubborn and loves to cause mischief. Spent most of her life surrounded by boys, making her a tomboy who avoids femininity. Genius engineer and fast learner (grasped a general understanding of robotics in a day from watching videos online.) Fluent in English and Thai.

Mischievous and rambunctious frog from Amphibia

Veronica Hill is a field news reporter working for Action News, a local news station in the Tri-State Area. A blunt and snarky news reporter who often weaves her personal issues into the current stories. Has brown hair and has brown eyes. She wears lipstick, a white shirt with a dark blue coat and dark blue skirt. Veronica Hill grew up on a family dirt farm. Veronica had desired to be a news reporter since she was a baby. Loves her stuffed teddy bear named Bearbra Walters.

This is an Action News special report!

Best friend of Milo Murphy and girlfriend of Zack Underwood. Good hearted, and very self-assured. A little scatterbrained. She's calm and controlled. A tremendous portion of her self-esteem depends on her school grades. A slender girl with light skin and wavy, shoulder-length ginger hair. Her large blue eyes have visible pupils, and she's usually seen wearing a smug expression.

Boom!

A pre-schooler chinchilla who is homeschooled by his parents. Fun-loving and imaginative, Chip can also be childish and overconfident, but has a good heart that always wins out at the end. He loves to play with his toys and play pretend. Chip is the middle child, and his family means the world to him. He looks up to his parents and will do anything to protect his siblings, even if he bickers with his older sister Charla a lot. Chip is interested in dinosaurs.