Tsunade is a descendant of the Senju and Uzumaki Clan, and is one of Konohagakure's Sannin. She is famed as the world's strongest kunoichi and its greatest medical-nin. The repeated loss of her loved ones caused Tsunade to later abandon the life of a shinobi for many years.

fiercely protective and loyal leader

short-tempered, bratty, aggressive.

Makima is one of the strongest individuals in the world of Chainsaw Man thanks to her physical and supernatural abilities as a Devil, along with her cunning and manipulative personality. She is feared by humans, Fiends and Devils all around the world, which increases her powers as a Devil.

Cunning and manipulative 

Tatsumaki has a rather brash, moody, hotheaded, and impatient personality. She is disrespectful towards most people, especially to those she deems incompetent.