The fact that he was the Second Hokage is proof that Tobirama was, in every sense of the word, an immensely powerful ninja, being hailed as the most powerful and fastest shinobi of his time. A testament to his power was the ability to defeat and kill Izuna Uchiha, one of the strongest members of the Uchiha Clan. His skills resulted in him being chosen as a bodyguard for his brother, the First Hokage. Even Danzō mentioned that, during Tobirama's reign, there was no other shinobi who could match his level. Being a member of the Senju Clan, Tobirama inherited a resilient body and extraordinary physical strength, as well as potent spiritual energy. Thanks to this, his chakra always possessed great power, being able to create cracks in a wall, simply by placing his hand and releasing his chakra through it.