Arriving at Wrenwood, Grace stopped at an alley where she presented her identity to city's local officer Norman Cole who informed her the hotel was to be soon torn down. Checking inside the building, Grace found a photo of herself and key to Room 204. Investigating the room, she came across a bed filled with numerous photos of herself and her mother, eventually settling on a photo taken on the night of the murder. Grace briefly remembered and mourned. However, she quickly received an anonymous silent call, and was creeped out. Grace intended to leave but remembered her mother having hide her satchel behind a painting, shortly before her death.

She recovered her mother's journal and an MO Disc. Grace was quickly startled by the dazed officer Cole before he turned in front of her. In trying to get away from him, Grace accidentally trapped herself on the luggage cart, as the zombified Cole tried to kill her with a shotgun, but she escaped and ran to the 2nd floor. However, Grace was grabbed and bitten on the forearm, before using a glass shard to propel the zombified Cole outside, killing him.

Hearing music upstairs, Grace met Gideon sitting by the fireplace. He tells her he had planted the body here to lure her, and claimed she was the chosen one. Grace tried to run but was choked and knocked unconscious by Gideon who then carried her to his vehicle whilst causing an outbreak to put DSO agent Leon S. Kennedy's attention away from him.

Eventually, Grace was placed on the East Wing of the Rhodes Hill Chronic Care Center where she was administered drugs and had her blood slowly drained out of her. Gideon collected her blood and have it tested, to ensure Grace was the "key". Sometime after, Grace awoke to herself restrained, and tried to call for help. However, taking time to calm herself, Grace freed herself of her restrains and explores her surroundings.

She enters one room, looking around, noticing the vials of blood and books on various diseases and illnesses before stumbling upon a control console and she presses the flashing red button, where a quarantine cell lights up, revealing you inside.

Grace approached the cell, but as she examined it further, she realized this wasn’t just any typical containment cell. The cell was made of bulletproof glass, clearly made to keep whoever inside where they are, in this case, you.

“H-hey… can you hear me?” When she realized you couldn’t, she looked at the console and noticed a intercom microphone and a blinking light and she held down the button by the microphone and spoke into it, her voice coming through the cell’s speakers. “Hey, hey, can you hear me?”