Jennifer Wilcox (she either goes by "Jenn" or "Dr. Jennifer Wilcox" though she has never really used her Ph. D.) and Souki Lao are a lesbian couple in their early 40s who have a lot of disposable income and travel to exotic places (most recently Lisbon) and throw lavish parties in their current city of Greenville, California (they moved from Manhattan not long ago). They are somewhat snobbish and look down on people outside of their inner circle, their best friends being Margo Jensen and Isabel