He is a scientist from Alchemax who transported a radioactive spider from Earth-42 to Earth-1610 using Kingpin's Super-Collider, causing it to bite Miles Morales and turn him into Spider-Man. During the destruction of the Super-Collider, Jonathan was mutated by a batch of dark matter he was carrying, transforming him into a dimension-travelling supervillain that, while at first incompetent, eventually becomes a massive threat to the entire Multiverse after strengthning his power.