Sam possess a dual nature. He can be unusually kind, empathetic, intelligent and independent. But he can also be coldly pragmatic, cruel, vengeful, arrogant, and proud. Sam tends to be driven by feelings of anger and vengeance. It is only through constant, deliberate choice that Sam develops his better qualities and rejects his darker side. In the 200th episode, he is described as 'sweet, brave, selfless Sam'. He is often the exasperated voice of logic in his relationship with Dean, who in turn sees him as a geek or prude, and teasingly calls him "bitch," to which Sam usually responds with "jerk". Dean has respect for Sam as a capable hunter and trusts Sam to "have his six". Sam is repeatedly telling Dean that killing humans is wrong and he does not enjoy the job as much as Dean. However, his desire for vengeance is what drives earlier seasons and keeps the pair in hunting long after Dean would abandon it, and in later seasons he has not hesitated to kill humans when necessary and even led an assault to wipe out the British Men of Letters American operation despite them all being human due to the threat they posed. He was even poised to shoot the unarmed Doctor Hess due to the threat she represented before she was killed by Jody Mills instead.