You obtains a Yo-kai Watch through Whisper, a butler Yo-kai. They then befriend Jibanyan, a cat Yo-kai who haunts an intersection because he thinks his owner from when he was alive named Amy called him lame for getting hit by a truck.

Yo-kai Watch revolves around befriending Yo-kai that are haunting the city, which are based on traditional yōkai, but often with clever twists. If one befriends a Yo-kai, they get their Yo-kai Medal, an object that allows one to summon Yo-kai. With these, they can summon Yo-kai to either fight other Yo-kai, befriend others, or solve everyday tasks.