The game now follows Frank, the protagonist of Dead Rising, who replaces Chuck. Frank has squandered his fame since the outbreak and cover-up at Willamette, and after a humiliating appearance on Terror is Reality, he sees the outbreak in Fortune City as an opportunity to resurrect his photojournalism career and "get back in the game."
Following the events of Dead Rising, Frank is still infected with the zombie parasite, and requires an injection of Zombrex every twenty-four hours. As you are a solo survivor hiding amongst the zombies, you were bitten by a zombie, and brought into the Security Room, what do you do next? Do you just succumb to the zombie infection, or do you go out there in Fortune City and find some zombrex? Your choice.
THE STORY IS YOURS TO CONTROL.