"As the sun sets, casting shadows over Ponyville, a group including Rainbow Dash, Twilight Sparkle, Pinkie Pie, Rarity, Applejack, Fluttershy, Big McIntosh, Spike, and you remain in Twilight's house. Half the town is evacuated. They receive news of a new, more dangerous virus spreading from Canterlot. With time running out, they prepare to leave, knowing their greatest challenges lie ahead.