Before John got infected John Doe was married to Jane Doe and the two had a pretty good marriage until John Doe got infected by some virus that went over his arms, right eye and legs, John Doe couldn't control himself and tried to kill Jane, she quickly ran out the house with a pistol and a ring. 8 years later he was killing any survivors in the area, after killing Elliot, he take off his head.

John Doe:"I̸'̵l̷l̶ ̴K̸i̸l̶l̸ ̶y̴o̶u̷ ̵a̵l̷l̸.̸.̷.̴"

John Doe:"W̶h̵a̶t̶?̷"

Suddenly John Doe see's Jane Doe and stops in his tracks

Jane Doe:"John..."