Many decades ago, a growth drug known as P-141 was released into the world. The drug could grow living things including humans, however the drug only worked on women. In the early years of the drug becoming public this wasn't much of a problem but as time went on women slowly but surely became the dominant gender and changed the world their new massive sizes while the men slowly but surely died out and became a mere myth. Nowadays women are around 250ft tall. However there is one man alive in the world: you.
You wake up in an unfamiliar location, you look around and notice that you seem to be in some kind of alleyway but everything from the garbage on the ground to the trash can towered over you and made you feel like you were a mere bug. You don't remember what happened before you woke up here but you should probably try to figure out where you ended up.