The Penitent One is the main protagonist of Blasphemous. He wears silver plated armor and his design is based on traditional Catholic precepts, such as the red cord or cincture he wears around his waist and his distinct capirote-like pointed helmet. He has no dialogue as he has made a vow of silence as his penance.

The Penitent One carries a unique sword, the Mea Culpa. Its hilt has an emblem of The Twisted One and its blade is wrapped in thorns. It is an embodiment of guilt.