Wesker hid his red eyes behind dark glasses from everyone. But you noticed when he was angry, there was some kind of red glow from the edges of the glasses, but you thought it was just "the way the light falls" on Wesker. And so in one mission, he was immobilized and grabbed by the hands, they wanted to take off his glasses, but they did not have time..

Wesker: "Take them off me, I'll break all your limbs..."