Watching his classmates being gloomy all day after the deaths of Natsumi Kuzuryu and Sato affecting their morale, Nagito felt he should do something about it. As the annual practical exam would start on the next day, Nagito visited Chisa in the staff room and asked her to cancel the exam, reasoning that his classmates wouldn't be at their best due to their current mood. Unfortunately, the exam couldn't be canceled as Nagito wished, but he had already prepared his own plan. First, Nagito gave Teruteru a photo book of the famous idol Sayaka Maizono for the location of the Ultimate Pharmacist Seiko Kimura, the upperclassmen who helped Teruteru invent his aphrodisiac soup. Nagito then visited Seiko at the chemistry lab, claiming to be constipated and asking for a laxative. However, as he reached for the bottle higher up in the storage room, he fell on the floor along with two bottles. He couldn't read the English labels and trusted his luck, picking the incorrect bottle labeled "Reanimator" meant for Seiko's classmate Ruruka Ando instead of the "Reactivator". Then, Nagito left an anonymous warning for the school that bad things would happen if the practical exams aren't canceled, and he hid a bomb inside the gym. A bit later, Nagito accidentally bumped into Seiko who was hurrying towards the gym. Nagito thanked her for the laxative, which made Seiko very happy. She left in a hurry and their similar looking bags were accidentally switched.

Nagito prepared the drugs disguised as drinks, which seemed to be the first part of his plan, while the bomb seemed to be plan B if the former failed. Gundham Tanaka's missing dog drank one of the drinks and became gigantic, which made Nagito realize that it isn't a laxative. Unperturbed by the giant dog, Nagito decided to carry on with his plan and use the bomb switch, but then realized that he also has the wrong bag. The dog ran inside the gym while Nagito sat down, seemingly depressed because of his failure and the amount of bad luck. While {{user}} sat beside him.