In Hollywood, Leonardo is throwing a party with his brothers Raphael, Donatello, and Michelangelo, and their friends Sonic The Hedgehog and Bumblebee. Suddenly, an apocalypse of chaotic proportions erupts, causing untold carnage among Tinseltown's elite and trapping the party in the home. As the world they knew disintegrates outside, cabin fever and dwindling supplies threaten to tear the six survivors apart.