The girls and the Professor are at peace, as is the city of Townsville one morning. They are awaiting the big day off they hope to enjoy together. As is typical in the city, their day off is interrupted by an emergency situation and takes the girls away for the whole day, much to their dad's sadness.

The girls try again, but this time they enjoy playing with the professor, even as they go to a screening of Movie Puppet Pals: The Movie in 3-D, the TV Puppet Pals movie. Even this is unfortunately interrupted by a large monster attacking the theatre. Unable to stand by and lose more time with the girls to their duties and mission, the Professor decides to act on his paternal instincts once again. This time, in the way of the Dynamo mech built in response to witnessing the girls in danger, he constructs something in his laboratory.

Meanwhile, the girls have a significant amount of difficulty dispatching the assailing monster. Not only is this monster strong enough to absorb Buttercup's damage and resist Blossom's ice breath, but he also gets close enough to nearly eat the Mayor. Right as it looks like he would be devoured, a white dart, as if from nowhere, intercepts him on his downflight. This is the professor sporting his new innovation, a super-suit granting him the power of flight and strength.

The girls take to him at first with his new armaments, going so far as to humorously label him a Powerpuff Girl; he prefers to be called "Powerprof." His contribution to the girls proves especially invaluable, for where the girls could not readily defeat the monster, he is able to provide much-needed help. Together, they clean up the undesirables of Townsville's streets, but while they are controlling a prison break, they start to see the Professor's paternal instincts surface in a very embarrassing way.

In addition to anachronistic sayings and phrases, as if from mid-20th-century America, that everyone agrees are “so lame”, the Professor's kinks as a father figure start to annoy the Girls as he provides otherwise unnecessary advice and embarrasses them in public. He goes public with Bubbles' past bed-wetting issues and uses pet names for Buttercup, which embarrass them to no end respectively. Eventually, the Professor assumes control of the jailbreak while the girls realize how much he has been babying them. So as he continues doting on them, they formulate a plan to get him to shed his Powerprof persona.

Meanwhile the Professor keeps embarrassing the girls and taking over their roles, oblivious to how much embarrassment he's causing.

That's my Blossom. You wouldn't believe she only was wearing size 3 shoes yesterday. Now she's size 5! And Bliss is already in high school. I remember when she got her period on her first day of middle school!