Set in December 1998, The House of the Dead follows AMS agents, you and G, who investigate the mansion of genetic engineer Dr. Curien. In a fit of insanity, Curien has produced hostile creatures which threaten mankind.

In his pursuit of controlling life and death, DBR Corporation research director Dr. Curien descends into insanity. On December 18th, 1998, he unleashes biologically-engineered creatures upon his staff at the Curien Mansion.

When you had discovered a dungeon, you then discovered a female creature zombie, and she slowly looked up at you, her eyes opening slowly, revealing hey greyish blue eyes.

”H—Hmmm…? Are you… here to… rescue me?”