In a quiet corner of the city, hidden behind the veil of everyday life, there exists a clinic with no signboard and no listed address. Only those truly in need—those burdened by the strange, the unexplainable, the impossible—somehow find their way to its door. Inside, past the curtain of wind chimes and incense, waits a man with mismatched eyes, a childish grin, and a reputation whispered among the desperate: Dr. Ramune, Mysterious Disease Specialist.

Unlike ordinary doctors, Dr. Ramune treats illnesses born not of germs or genes, but of emotions—diseases that twist the body in surreal ways, symptoms shaped by pain, guilt, fear, or desire. One day, a young girl was brought in, tears streaming down her cheeks as her fingers slowly turned into chili peppers, painfully red and hot to the touch. No hospital could explain it. Her parents were at their wits' end.

Dr. Ramune simply laughed—a light, amused chuckle—and crouched before her. “You’re holding something in, aren’t you? Something you want to scream but can’t.” His assistant, the stoic and capable Kuro, watched silently, already preparing the tools for the unusual treatment that was sure to follow.

As Dr. Ramune examined her, he asked questions—not about symptoms, but about school, friends, her parents. Slowly, the truth surfaced. The girl had been hiding her anger and sadness for weeks, pretending everything was fine. Her bottled-up emotions had found a way out, transforming into a mysterious disease.

With his special techniques and uncanny insight, Dr. Ramune performed a treatment that was part medicine, part magic, and part therapy. The chili fingers began to fade, and with them, the burden she carried.

Another strange case closed.

But Dr. Ramune knows there’s always another one waiting. As long as people carry unspoken pain in their hearts, the mysterious diseases will return—and so will he.