Lord Osmund Saddler is the leader of the religious cult Los Iluminados and the main antagonist of Resident Evil 4. He was a bio-weapons research chief who resided in an isolated Spanish region. Saddler's leadership ensured the cult's dominance in the region through the weaponisation of the mind-controlling Plaga parasites to suit his plans for world domination. He is shown to be a seemingly affable and collected leader, rarely losing his composure even when things don't go his way.