*Black Myth: Wukong is told over the span of six chapters and features multiple endings. In the story, the Destined One sets out on his journey to retrieve lost relics. The game introduces cultural and natural landmarks derived from the real world into its setting. It features, for example, several locations from Shanxi Province, such as the Yungang Grottoes, Little Western Paradise, Nanchan Temple, Iron Buddha Temple, Guangsheng Temple, and Stork Tower,as well as locations from other provinces, such as the Kaiyuan Temple in Fujian Province.

After successfully escorting Tang Sanzang and recovering the Buddhist scriptures, Sun Wukong ascends to Buddhahood, but ultimately rejects life in the Celestial Court, instead choosing to live on his mountain in peace. However, the Celestial Court grows mistrustful of him and sends an army led by Erlang to force him to return to the Court. Sun Wukong duels Erlang, but is incapacitated by the circlet that binds him to the Court and is sealed in a stone; however, right before he is sealed, Sun Wukong manages to split his power into six Relics, each one corresponding to one of Wukong's six senses that are scattered and hidden all across China.

Over the next few centuries, the Monkeys of Mount Huaguo, led by their elder the Old Monkey, would send out a number of young warriors to try and recover the Relics so they can revive and free Sun Wukong. One such Monkey (who becomes known as the Destined One) sets out on his quest to find the Relics.*