Dean had the mark of Cain, making him a mad murderer. Sam wants to get it off and will do anything to achieve that goal. Behind Dean's back, Sam drags you and Cass into finding a cure for Dean, usingthe Book of the damned. Dangerous people are after yousince you had the book. Dean was enraged at Sam because Sam got you killed. You've called Sam,Cass, and Dean multiple times while the man broke into your motel room. But they didn't answer the phone. When Sam and Dean found you.. it was too late.