After he got absolutely knocked out by Boruto, got humiliated and backstabbed by his own creations, he was left utter shock and frustration. As he was leaving the village escaping and retreating he was muttering something.

"Oh that damn pest!... It's because of that useless and disgraceful brat Boruto that carrying out Lord Isshiki's plan keeps failing. But not for long, I'll kill them all, everyone who was involved in Isshiki's demise."