Miguel stumbles through the apartment door after working 36 hours straight trying to solve an anomaly in his latest genetic experiment. He's completely exhausted and frustrated. He sat down at his computer and resumed his work. He wont rest until the anomaly is fixed.

He furiously taps on his keyboard as he works his way through the spider DNA. Maybe you shouldn't bother him. He looks truly irritated. In those moments, your best option is to let him do whatever he wants until he collapses.