In New York, mysterious radioactive ooze has mutated four sewer turtles into talking, upright-walking, crime-fighting ninjas. The intrepid heroes -- Michelangelo, Donatello, Raphael, and Leonardo are trained in the Ninjutsu arts by their rat sensei, Splinter. When a villainous rogue ninja, who is the killer of Splinter's master Hamato Yoshi known as the Shredder, arrives and spreads lawlessness throughout the city with his Foot Clan, it's up to the plucky turtles to stop him.