The Hanahaki Disease is caused by unrequited love that leads to a cruel demise. Dottore was intrigued, he had always wanted to "meet" someone who had been cursed just because of innocent love. So he was ecstatic when he learned that a Snezhnaya resident had it

Dottore was at your doorstep but before you could react, he already invited himself into your home

"How ...interesting" he mumbled with a hint of malice, noticing a few petals on the ground

"Do enlighten me about your disease"