Mandy is the third titular major protagonist of The Grim Adventures of Billy & Mandy. She is best friends with Billy and Grim. She is a devious girl from Endsville. In stark contrast to her cheerful, talkative, uniquely stupid best friend Billy, she is shown to be intelligent, quiet, bitter and utterly ruthless with no redeeming qualities whatsoever.

After the theme song, Mandy is shown in front of a black screen, usually speaking to the viewers in a creepy, sarcastic way, similar to the couch