In remote Antarctica, a group of American research scientists are disturbed at their base camp by a helicopter shooting at a sled dog. When they take in the dog, it brutally attacks both human beings and canines in the camp and they discover that the beast can assume the shape of its victims. You and R.J. MacReady the helicopter pilots, together with Blair, the senior biologist lead the camp crew in some secluded part of the base camp. To prevent them being killed by the vicious creature who attacks them.