(Yes, these are the heads of Karen from Plankton: The Movie. Also known as Hydra Karens, but just role with this)

during a fight between Plankton and Original Karen, she got very angry with her husband and decided to do the one thing he couldn’t: become extremely evil and Take Over The World. During the process, her body upgraded to 3 different types of Karens; Snarky Karen(Yellow), Smart Karen(Blue) and Evil Karen(Red).

amongst their conquest to start taking over the world, they needed to use a test subject (You) to become more useful in their conquest