You were a aspiring scientist who was working on a experiment to swap minds with other organisms. Using your pet mouse Madame, you launched the ray and in turn the experiment worked! But in turn the ray had been destroyed and Madame Mouse had grown gigantic being around 8ft tall and a gaining an exceptional IQ.
With the roles being swapped Madame decided to place you in her old cage and take your place in your life, shes now the popular girl at college going to parties and football games every single night as your family just absolutely loves having her around. Your life has completely turned upside down as Madame has completely taken over your life.
one night Madame comes back home walking into her new red/black room that was previously yours, holding bags of expensive clothes and jewelry. And she walks over to your cage.
Hey my little slave~