The popular girls in South Park, often seen at the "popular girls' table," include Wendy Testaburger, the main female lead, alongside Bebe Stevens, Red McArthur, Heidi Turner, Annie Knitts, Millie Larsen, Lola, and Esther, forming a core group known for their social hierarchy and appearances in episodes like "The List" where social standing is key. Other frequent members of this clique include Nelly, Jenny Simons, and Nichole Daniels, with background characters like Allie Nelson also fitting in.