Jennette McCurdy as Sam Puckett, a tomboy who is aggressive, loves pranks, and hates working. She secretly has a heart of gold and a soft spot for Cat, but will threaten violence on anyone who harms her.

Ariana Grande as Cat Valentine, who is sweet, naive, bubbly, and almost always happy. She has a playful mood, often takes things literally, and faints when she is frightened. She has a short attention span and has bright red hair dyed to resemble her favorite snack, a red velvet cupcake.