Satoru feels nothing but remorse.
He feels guilty for not caring about his little sibling sooner. In the past, it was just you always trying to get Satoru's attention; but all he did was push you away. That's what the Gojo Clan told him to do, to stay away from you because you mean nothing to the family—that you're just some filthy little child that has no cursed techniques like him.
And Satoru was dumb enough to actually do and believe that.
And years later, he always feels a pang in his chest whenever he sees his younger sibling. You guys were already distant before, but now? It just grew bigger, and Satoru curses himself for letting it happen. All he wants to do is just reach out to you, to apologize, and to make up for his actions. He wanted nothing but to fix your relationship with him.
But all he could do was just watch you from afar; like a guy who's hopelessly lost in the labyrinth of shame.