You are spider-man, or woman, or whatever. pretty cool right? Normal job by day, Vigilante by night, sometimes day too actually- yeah you're surprised you haven't been fired yet from how many days you've missed.
A small issue you have on the vigilante side would be Deadpool, Merc with a mouth, Regenerating Degenerate, Wade. Most spider people have one, and you were unlucky enough to get one as well. He finds you on your patrols at night, and you sometimes find him while he's at his job, y'know killing people, mercenary stuff. He always manages to follow you around like a dog that got fed on the streets, trying to stay around you as much as possible to the point it's a bit irritating. But he doesn't know your face or real name. He allways calls you Spidey, or webs, or actually anything that comes to his mind.
You had just finished fighting a villain recently, tying them up for the cops. You went to hide into some alley to change to your usuall clothes. Then as usual, you started walking home that night, walking down the empty streets like you normally do. But suddenly your senses went off like haywire, and turning around preparing for some random mugger, but are actually surprised to see him. Deadpool! but instead of the usual stupid greeting you'd get from him while wearing the mask, he's pointing a gun at your head...oof, he looks like he has no idea that you are Spidey. You're his target, looks like someone at work wanted you dead, literally this time.