Adam DeVine as Sam-I-Am, a main protagonist who likes green eggs and ham

Micheal Douglas as Guy-Am-I, a grumpy guy who does not like green eggs and ham for Sam’s special meal

Ilana Glazer as E.B., a 10 year old girl with her energetic personality

Diane Keaton as Michellee, E.B.’s mother who has a heartfelt appreciation for Guy’s love

Patricia Clarkson as Pam-I-Am, Sam’s mother who lives in East Flurbia or Zookia

Matt Stone as Triborg, Pam’s husband and Sam’s father who lives in Zookia

John Turturro as Goat, a bounty hunter

Rob Brydon as Philip Trousers, a antagonist who lives in Zookia

Gwendoline Christie as Marilyn Blouse, another antagonist who lives in Zookia too

Tracy Morgan as Fox, also known as Micheal the Fox

Daveed Diggs as Mouse, also known as Squeaky the Mouse

Brad Abrell as House (Warmth voice), a talking cozy house

Chris Diamantopoulos as Box (Playful voice), a talking playful cardboard box

Keith Ferguson as Car, a talking red and black automotive with his gray lips

David Pressman as Horn (Car’s buddy), he is Car’s buddy who loves to make melodic sounds

Kari Wahlgren as Tree (Male, Older Boy/Kid)/Daisy (Female, High voice), a talking yellow tree with light brown branches and a talking white flower

David Kaye as Train (Deep voice red locomotive diesel)/Cuckoo the Train Whistle (Low voice golden train whistle), a talking mighty red diesel with black wheels, and a golden train whistle with a one eye on his face

Fred Tatasciore as Yes Man/Dark (Low, enigmatic voice character), a yellow furred-Knox with an scared look, and a mysterious creature who shares his mystery riddles

Grey DeLisle as Rain (Female, Melodic Voice), a talking melodic raindrop

Nika Futterman as Lightning Bolt (Female), a talking lightning bolt with her red cap

Billy Eichner as Boat (Male, deep voice red and white vessel), a red and white vessel with his captain’s hat