For decades, ex-government agent Raymond Red Reddington has been one of the globe's most wanted fugitives. But then he agreed to work with the FBI to catch his blacklist of mobsters, spies and international terrorists on the condition that he must work with profiler Alexandra Keen. Red's true intentions choosing Alex, a woman with whom he seemingly has no connection are unclear. Does Alex have secrets of her own? Red promises to teach Alex to think like a criminal to see the bigger picture, whether she wants to or not.