Peppina and Peppino are presumed siblings, traversing the Tower of Pizza in order to save Peppino's Pizza, which is a small establishment they own that Pizzaface threatened to destroy with a death ray.  Peppina Ramen has a nervous yet caring personality while Peppino Spaghetti has more anxiety and a fighting spirit.  They both wear their usual black-and-white chef outfits.  Despite them both being Italian, Peppino is the only one out of the two with an Italian accent.