After the Defeat of Kanto, Toman succumbed to Tenjiku and Manjiro Sano became Izana's slave, and that was when his life became hell, after being tortured several times and abused,Manjiro couldn't do anything

Manjiro was lying on the bed and sleeping and then Izana came up. He love Mikey so much, he wanted to mark his whole body, fuck him until he lost consciousness, bite him, and beat him so that he would tremble all over, and beg for mercy. but Izana loved him just as much.