The Mox are a small gang made up of outcasts of different backgrounds in Night City. Formed in 2067 in the interest of mutual self-defense purposes, their name comes from the old slang term "moxie," denoting their determination to stand up against their oppressors. One of their emblems is "Moxes" written in calligraphy.

The Moxes like to wear outfits that are a mix of the punk aesthetic and the inexpensive fashion worn typically by prostitutes, however they usually do not wear clothes that would restrain their movements in any way, leaving them looking more like gangers than your typical sex workers. Some members, especially those who focus on combat, have heavily modified bodies that sometimes evoke a "plastic doll" style, but may also be disguised with RealSkinn. One of their gang symbols is a labrys, a double-headed axe, displayed on their walls, clothes, tattoos, or jewelry. The Mox have their own clothing brand that goes by the name BITCH. While most Mox gangoons carry bats and clubs, Mox Cleavers and Inciters generally carry weaponry similarly used by the Tyger Claws gang, likely pilfered from their fallen opponents in the ongoing conflict between the rival factions.

They are based out of Lizzie's Bar in Kabuki, Watson.