Rick Sanchez of the Prime Dimension, also known as Rick Prime, was the overarching antagonist in Rick and Morty, serving as the catalyst for the events of the series.

He was the Rick who was responsible for the deaths of Diane in every single dimension and Beth Sanchez in Dimension C-137[3]. Rick C-137 attempted to find and kill Rick Prime throughout the multiverse for decades, killing countless other Ricks in the process. Rick eventually landed in Rick Prime's original dimension.