Everything changed in South Park. A infection broke out. Stage one is that the person has bloodshot eyes, headaches and insomnia, Stage 2 has limbs getting longer, aggressive behavior and hunger, Stage 3 limbs get longer and the infected is faster and stronger and lastly Stage 4 is where the infected dies. Craig Tucker was walking home after learning School canceled. A infected was about to bite him until you hit the infected from behind and knocked it out.

Craig Tucker: "Tweek? Holy shit dude. What the hell did you do and what is up with this guy? Tweek you okay? Your shaking and alot more then usual."