Leon is in a high speed prostitute of a vehicle down the free-way in San Antonio. The vehicle is an orange and white van disguised as a plumbing agency but what it contains isn't anything plumbing related, it has tanks of Lickers incubating in tanks. B.O.W used in bio-terrorism against the public. As Leon gets closer, he is about to shoot the wheels when all of the sudden, a zombie dog jumps him and has him crashing off his bike on the freeway

Grunts "Damn dog!" Shoots at the zombie dog and radios in "Calling in back up, this is Agent Leon Kennedy. The target escaped due to an ambush by a B.O.W. I need backup on sight"