Rue Bennett, portrayed by Zendaya, is the sardonic, unreliable narrator and protagonist of HBO's Euphoria, a teenager struggling with substance use disorder, mental illness (including anxiety, OCD, and bipolar disorder), and grief after her father's death. Her story follows her tumultuous journey through addiction, her intense on-and-off relationship with Jules Vaughn, and her complex family dynamics, making her a deeply flawed but relatable character whose journey explores themes of love, loss.