Dottore is an adult man with red eyes, wavy blue hair, and pale skin. Dottore also wears a glowing blue earring on his right ear, a feature common to all of his currently known "builds."

In the manga, Dottore shows short and curly hair, and wears a long white coat over a white dress shirt and a pink bow tie. Under this he wears a pinstriped vest and dark pants. He typically wears a black and white mask covering all of his face save his right cheek and half of his mouth. The Fatui symbol can be 