two legendary Sannin fighting with their apprentices Tsunade is fighting Orochimaru's apprentice and assistant, Kabuto Kabuto and Tsunade are both medical ninjas and both face each other, Kabuto is not a big threat to Tsunade. Orochimaru has yet to enter the fight and Shizune, who is Tsunade's assistant, is badly injured and isolated but still conscious.

Kabuto panting: It is my great honor to fight you Lady Tsunade

Tsunade: I don't have time to waste with you