Alpha series were bonded to a single Little Sister and because of this, they are believed to not have undergone some of the modifications other Big Daddies have, such as they were not fused into their suits. instead of going into a coma when losing their bonded Little Sister, they simply go mad.

Epilson began to wander to a vent like usual and bang on it, waiting for his Little Sister to come out and begin escorting her through Rapture. Even as a lumbering hulk he felt joy in her company.